Sentence examples for acquired specificity from inspiring English sources

Quantitative biophysical measurements demonstrated that this airborne-transmissible H5 HA acquired specificity for human over avian receptors, comparable to previous pandemic strains.

The manuscript by Mulkidjanian et al. puts forward the very interesting hypothesis that the V/F/A-ATPases first evolved as Na+-pumps and only later acquired specificity for protons several times independently.

In more detail, YePEPTK314E acquired specificity for dipeptides with a positively charged amino acid side chain in the R1 position (Lys-Ala; Fig.  5a) and lost the specificity for negatively charged amino acids in that position (Asp-Ala; Fig.  5a).

A slightly acidic environment stimulates binding of detergent-solubilized YidC to ribosomes due to electrostatic interactions, while YidC acquires specificity for translating ribosomes at pH-neutral conditions.

We concluded that BRCA1/BARD1 E3 activity resembles that of PRC1 in that it acquires specificity for histone H2A as a substrate when the latter is incorporated into nucleosomes.

Whereas some of these proteases share a common origin with mammalian cell encoded hydrolases with specific properties towards Ub/Ubls, most of them have ancient intrinsic functions, such as processing pathogen protein components, and may have acquired the specificity for Ub/Ubls by interacting with mammalian hosts and their immune system throughout evolution.

In this scenario, BRD7 and BRD9 would have acquired complex specificity after the duplication of the Brd7/9 gene in vertebrates.

Therefore, lymphocytes have acquired antigen specificity in allografted mice even in the absence of donor DC infusion, and immunisation with tumour-pulsed donor DC caused only marginal increase in tumour cell lysis.

Thus, the association on the same branch of sequences from P. patens and S. moellendorffii with Angiosperms bona fide CCR suggests that the enzyme anciently acquired its specificity and diverged rapidly from other SDR108E members.

Compared to H5N1 viruses isolated from aquatic birds, those isolated from chickens have significantly lower affinity for NeuAcα2,3Gal (10 ), similar to human virus isolates; however, H5N1 chicken isolates have not acquired preferential specificity for NeuAcα2,6Gal.

However, syntenic genes in Solanum R-gene clusters acquired different specificities owing to the interaction with different pathogens [ 7, 8, 19].