Exact(9)
Whole body scintigraphy was acquired on day 6 to 11 (median 7 days, range 6 to 11), and in one case also at 17 days p.i.
Participants were shown 36 out of 52 faces in total, with half of them acquired on day 1 around 24 h before the task (that is, overnight condition) and the other half acquired on day 2 about 30 min before the task (that is, newly acquired condition).
In the TNT Phase, participants underwent fMRI with concurrent recording of SCRs while performing the TNT task for face-picture associations acquired on day 1 and day 2. Each trial started with presentation of a face for 4 s, and was followed an inter-trial interval with a fixation cross for 2 6 s (average duration=4 s).
A first set of hematology parameters, liver and kidney values and electrolytes was acquired on day 3 5 after therapy administration.
A PET image acquired on day 14 is shown in Fig. S4 and ex vivo tissue uptake data for both radionuclides at 7 days are listed in Table 3.
Tumor boundaries were defined on the image that was acquired on day 0 and the area of tumor cell invasion of surrounding extracellular matrix outside this region of interest was then determined at subsequent time points.
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