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Although platinum therapy has been a major advance in improving patient outcomes, the development of treatment-related toxicity and the emergence of resistance (both intrinsic and acquired) limit the effectiveness of platinating agents in solid tumours (Siddik, 2003; Rabik and Dolan, 2007).
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Hydrolyzed D70-g-PAA copolymer in a salt form acquired limited extended conformation due to appearance of charged functional group.
Acquired limits of errors for deflection magnitude and deflection direction measurement are ±0.15 mm and ±2.5°, respectively.
However, inside this group, there are some countries that are self-sufficient in terms of energy and that are, in fact, energy exporters; these countries, despite their high rates of population growth, have acquired limited foreign areas.
The Oprah Winfrey Network, continuing its programming pivot, has acquired limited rights to the beloved daytime dramas "All My Children" and "One Life to Live".
Changes affecting actin cytoskeleton architecture were early events in the transitional progression of our MOSE-derived cells as most of the changes in gene expression and protein levels were readily evident in the MOSE-I cells, an intermediate transitional stage that already has acquired limited tumor-forming capacity.
Students acquired limited prescribing competency during the PBL programme.
Interestingly, the recently emerged Rap1 retrogenes acquired limited amino acid-changing substitutions and our statistical analysis favors a scenario whereby they evolved under selective constraints on coding sequence.
We characterize here two murine-specific Rap1A retrogenes and one human-specific Rap1B retrogene that acquired limited substitutions in amino acids, including the residues G12 and A59 that were found to be mutated in oncogenic Ras isoforms.
EU carriers will, for example, acquire limited rights to carry American government-funded passengers and cargo.
In our studies, we acquire limited MRI sequences, which reduce the cost of research.
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