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Immune thrombocytopenia (ITP) is a relatively uncommon auto-immune disorder in childhood (estimated incidence of 4 to 5 per 100,000 person-years) characterized by an acquired decrease in circulating platelets [ 1, 2].
A series of pediatric investigations support the notion that a hospital acquired decrease in p-Na+ in ill children receiving parenteral fluid therapy is the result of administering an excess of water relative to sodium, i.e., hypotonic saline solutions [ 6, 7].
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The acquired decreased binding capacity of neutrophils may be detrimental in sepsis and may even be aggravated by the increased circulating levels of glucocorticoids.
Hypothyroidism will most often lead to hypocoagulation [ 41, 42] related to a decreased number of platelets due to increased turnover time and inhibition of megakaryopoesis and acquired decreased concentration of vWf-ag [ 11].
This mix of clones with different susceptibility causes a trailing endpoint in MIC distribution diagrams and difficulties to define a wild type cutoff value to separate the wild type from isolates with acquired decreased susceptibility.
My first point regards the mechanism by which methicillin-susceptible Staphylococcus aureus (MSSA) with reduced susceptibility to vancomycin would also acquire decreased susceptibility to β-lactams.
The incidence density of ICU acquired MRSA decreased significantly by 29% over the four year period in these ICUs.
Overall, the risk of developing hospital acquired VTE decreased significantly after implementation (RR 0.69, 95% CI 0.47 to 0.79) while the risk of developing preventable VTE decreased by 86%95%5% CI 0.06 to 0.31) (table 6).
However, the quality of the acquired data may decrease due to adverse climatic condition (such as clouds) [3].
Newly acquired sequences can decrease host fitness unless integrated into existing genetic regulatory networks.
Effective bacterial EPIs should reduce the intrinsic resistance of bacteria to antibiotics, reverse any acquired resistance and decrease the frequency of emergence of resistant mutant strains [ 17].
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CEO of Professional Science Editing for Scientists @ prosciediting.com