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Calculated free energy decomposition per residue and acquired backbone chemical shifts agree on the impact of individual IL-8 residues for GAG binding.
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Here, NMR relaxation parameters were acquired for backbone 15NH groups of the 56 residue immunoglobulin-binding domain of streptococcal protein G over a pre-denaturation temperature range of 5 50 °C.
Two-dimensional (2D) N−H HSQC, three-dimensional (3D) HNCACB, 3D CBCA CO NH, 3D HNCO, and 3D HNHA spectra were acquired for backbone assignment.
For V22-SH3, NMR spectra were acquired for both backbone and side chain assignments which included 15N-edited HSQC-TOCSY, HSQC-NOESY and 13C-HCCH-TOCSY as well as triple-resonance experiments [HNCACB, CBCA CO NH, HNCO].
End-sequences were acquired, the vector backbone was masked out, and the remaining sequences were assembled.
Akamai's chief executive, George Conrades, is a former head of IBM North America who went on to run BBN Corp., an Internet backbone later acquired by GTE.
X-ray diffraction analysis showed that for compounds 2a and 2c a non-planar conformation for the main π-backbone is acquired after boron complexation; for compound 2b the planar conformation is preserved.
The first is that by acquiring the software "backbone" powering travel search, Google will be able to squeeze out its rivals over time.
The VTI unit owns S⋯OC intramolecular noncovalent interactions, which is favorable for acquiring planar conjugated backbone, thus leading to enhanced semiconducting properties.
Last year with a partner it acquired a Canadian long-distance backbone called Teleglobe, with $1 billion in revenue, for $155 million.
The company is led by serial entrepreneur Craig Walker and other execs who built Grand Central, which Google acquired and made into the backbone of its Google Voice product.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com