Sentence examples for acquire new functions from inspiring English sources

As noted by Haldane [1], and Ohno [2] the products of such events may acquire new functions (neo-functionalization), survive due to dosage effects (sub-functionalization), become dysfunctional due to mutational insertions, deletions and/or substitutions (pseudogenes), or be lost, without obligate deleterious effects to the host.

It has been proposed that duplicate gene copies may 1) accumulate nonsense mutations in regulatory or gene elements and become non-functionalized, 2) diverge in the tissue or timing of expression compared to the ancestral copy and become sub-functionalized, or 3) acquire new functions and be neo-functionalized [ 30].

Duplicated genes are generally free to evolve and acquire new functions, which can confuse functional attribution by sequence similarity.

Dubbed as neofunctionalization, one of the two duplicated genes can be released from functional constraint and acquire new functions, whereas the other gene performs the original functions (Innan and Kondrashov 2010).

Addition of new domains would permit these enzymes to acquire new functions and specificities contributing to the functional diversities of these gene families.

In other cases, soils of urban areas acquire new functions that are unique to these environments.

Second, both copies of the genes may be retained and share the ancestral function, but gradually develop partially different functions (sub-functionalization). Third, one copy of the gene may acquire new function(s) during the course of evolution (neo-functionalization).

Hence, gene duplication with subsequent diversification is one of the simplest ways to acquire new function.

Furthermore, bi-paratopic BsAb, by simultaneously binding to two different epitopes on the same target molecule, could even potentially acquire new function that could not be achieved with the parent antibodies when used alone or in combination [56].

Such inactive enzyme homologues are present in many enzyme families and are believed to acquire newer functions during evolution [ 29, 30] (Additional file 1).

Duplicated genes contribute to functional innovation, with the redundant duplicate often acquiring new functions that derive from an existing secondary function (Conant and Wolfe 2008).