In June 1956, for instance, during the regular editorial lunch at the Waldorf Hotel, Crankshaw, not revealing his source, mentioned that he had acquired a transcript of Khrushchev's secret denunciation of Stalin to the 20th Communist party congress.
Thus, Cdx2 transcripts acquire a polarized distribution preceding ICM and TE lineage segregation.
The response of chicken RNAi machinery against exogenous L1s seems to be more subtle than that of some other eukaryotes such as mouse, C. elegans and Drosophila, whose genomes can rapidly accumulate retrotransposon transcripts and acquire a mutator phenotype through disruption of RNAi pathway [ 20, 28].
It remains to be determined whether the incompletely capped transcripts are generated as a consequence of intrinsic stochastic inefficiency of the capping process or an indication that capping is normally a regulated process in which not all primary transcripts are destined to acquire a methylated cap.
Other functions of Rat1 include degradation of some splice defective pre-mRNAs (Bousquet-Antonelli et al, 2000), transcripts that fail to acquire a cap (Jimeno-Gonzalez et al, 2010), RNA transcribed from telomeric repeats (Luke et al, 2008) and promoting transcriptional termination of Pol I (El Hage et al, 2008; Kawauchi et al, 2008).
Based on gene expression studies, an authentic transcript tends to be maintained the major function, whereas a minor transcript tends to be free from selective pressure and ready to acquire a novel function31.
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As a first step, two researchers (M.I.Z. and M.G). each read five transcripts in full to acquire an overall picture of the situation.
For algorithms providing site-level predictions (i.e., ElMMo, MBSTAR, miRSVR, PITA, and RNA22), scores were summed within genes or transcripts (if available) to acquire an aggregate score.
An SV40 late region polyadenylation sequence occurs downstream of the cDNA cloning site, so that the cDNA transcript acquires a polyadenylated 3' end.
