Exact(1)
Given the inducible nature of this model, it was natural to ask whether cells acquire a dependence on AML1-ETO expressior or whether disease continues and progresses even upon termination of this signal.
Similar(59)
Analysis using BH3 profiling confirmed that spheroids acquired a dependence on anti-apoptotic Bcl-2 proteins and were 'primed for death'.
We show that in addition to the citrate-catabolizing strain, three other lineages evolving in parallel have acquired a dependence on citrate for optimal growth on glucose.
By performing high-throughput loss-of-function genetic screens that exploit RNA interference technology [ 58], Gilliland and colleagues [ 59] showed that tumor cells with mutant RAS have acquired a dependence on the kinase STK33; tumor cell molecular networks have been rewired such that STK33 now becomes critical whereas it is not in normal cells.
This is a very rich structure, which has been shown to recover a variety of important quantum wave equations, as soon as the Euler angles are allowed to acquire a space-time dependence [12].
Patients with critical illness can acquire a syndrome of weakness and dependence on mechanical ventilation that has been linked to peripheral nerve and muscle injury.
Acquire a college education.
Also, acquire a barrel cover.
Acquire an eye patch.
Acquire an ice cream maker.
We therefore assume that the DEB025res genome lowers CypA dependence by acquiring a conformational inversion mediated by the D320E mutation, that otherwise is supported by CypA.
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