Sentence examples for acknowledged animal model from inspiring English sources

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Therefore, it is reasonable under experimental aspects to use porcine test specimens, because porcine knee joints resemble the human knee joint anatomically [ 57] and are a well acknowledged animal model [ 13].

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Finally, it must be noted that the consensus of the eighth European workshop on periodontology has acknowledged that "animal models may not completely recreate the anatomical, physiological, biomechanical/functional, or pathological environment of the clinical conditions in humans" (Berglundh & Stavropoulos 2012).

In considering the clinical implications of these studies, it is important to acknowledge that animal models of ARDS do not fully replicate the complex pathophysiological changes seen in the clinical setting.

Finally, we must acknowledge that our animal model of sepsis, like sepsis in humans, is associated with a variable inflammatory response (Table 1).

Whilst acknowledging the limitations of transferring data from an animal model to a clinical environment, by providing the first data and equations detailing the film thicknesses and lubrication regime for these two tendon regions it is hoped that clinicians, engineers and scientists can consider improved clinical strategies to tackle both tendinopathy and tendon rupture.

We acknowledge that biological findings in cell lines and animal model systems have not always validated in human tumors.

By the 2000s, the pharmaceutical industry was acknowledging the inability of animal models to predict human response [ 117].

We would like to gratefully acknowledge the expert advice provided by Dr. R.T. Zoeller in the development of this animal model, and for very helpful discussions.

Tau poly-ubiquitination is acknowledged to be a late process in the pathogenesis of Alzheimer's disease and in an animal model of tau pathology [48,49].

However, one of the major shortcomings in this area – and one that has not yet been rigorously acknowledged – is the lack of animal models that accurately recapitulate key features of the human disease.

Table 3: Animal model of MDD.

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