Sentence examples for acidification function from inspiring English sources

And the value of CO2 can evaluate the acidification function of the renal tubule.

Notably, a v100 cDNA carrying a mutation that blocks its acidification function in the V-ATPase still rescued degeneration as well as the wild-type v100 cDNA.

Another example can be found in calcium phosphates, which constitute a very heterogeneous group with multiple etiology including infections (in the case of carbonated calcium phosphate and whitlockite), hypercalciuric mechanism (in the case of brushite and octacalcium phosphate), and disorders related to tubular acidification function (in the case of carbonate apatite).

5, 22 It has long been recognized that SC acidification functions as a defense against microbial invasion, as it was shown that an acidic pH inhibits the colonization of pathogens such as Staphylococcus aureus and Streptococcus pyogenes while encouraging the growth of normal skin flora.

In addition, our results suggest that the site 8 region is not essential for the de-acidification function of urease, but rather is involved in an alternative function required for persistence of infection in the host.

To demonstrate autophagic flux, meaning autophagy that proceeds through to lysosomal degradation without blockage, inhibitors of lysosomal acidification and function, such as bafilomycin A, chloroquine (CQ), and hydroxychloroquine (HCQ), are commonly utilized in in vitro settings.

The vacuolar ATP-ase acidifies endocytic organelles, but v100 has an acidification-independent function regulating SNARE-mediated membrane fusion.

So, it is possible that UNC93B1 might regulate pH acidification through TFEB function.

Discovery of mutations in OTM-associated genes of orthodontic patients, including those regulating osteoclast bone-matrix acidification, chloride channel function, and osteoblast-derived mineral and protein matrices, will permit gene therapy to restore normal matrix and protein synthesis and function.

Chloroquine accumulates in the lysosome and prevents acidification, impairing protease function.

53 A more recent study has shown that in filaggrin-deficient ft/ft mice, sPLA2-IIA is upregulated along with NHE1 expression, while sPLA2 forms -IIF and -X do not, 1 contrasting with a previous study that demonstrated that sPLA2-IIA does not contribute to acidification and barrier function and sPLA2s-X is the main isoform to be secreted from keratinocytes.