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Discover LudwigThe phrase "acidic tissue" is correct and usable in written English.
It can be used in contexts related to biology, medicine, or chemistry, particularly when discussing the pH levels or characteristics of certain tissues in the body or in other organisms.
Example: "The acidic tissue in the stomach plays a crucial role in digestion by breaking down food and killing harmful bacteria."
Alternatives: "low pH tissue" or "tissue with high acidity".
Exact(3)
An acidic tissue microenvironment is also correlated with energy metabolic dysfunction, mainly because a high rate of glycolysis generates a large amount of lactic acid, which promotes the generation of acidic tissue microenvironment [56].
Acidic tissue hydrolysate was neutralized to pH 7.0 and mixed with 10 mM CuSO4 and 2.5 N NaOH followed by 6%H2O22.
The lower p Ka of nitrodopamine likely contributed to a higher amount of oxidized species (i.e., semiquinone), which aided in its transition to quinone for reaction with amine group even if there is a higher amount of protonated −NH2 on the surface of an acidic tissue.
Similar(57)
The peptide targets acidic tissues in vivo and may be useful in cancer biology for delivery of imaging or therapeutic molecules to acidic tumors.
On the other hand, the "slightly acidic tissues" in carrots would lose some acidity to the water.
This may potentially reduce unwanted drug release at non-cancerous acidic tissues leading to eliminated side effects.
Most recently, there has been intense effort on the uses of a pH dependent membrane insertion peptide to image and deliver molecules to the cells in acidic tissues, including tumors.
In acidic tissues, such as tumors, peptides in the pHLIP family insert as α-helices across cell membranes.
Under these conditions, the excess of nitric oxide in blood can be taken up by PEG-albumin to be redistributed and then released in hypoxic or acidic tissues.
Because of their pH-dependent interaction with membranes, pHLIP peptides have been shown to target and persistently label cells in acidic tissues, such as cancerous tumors, in vivo.
Acid-degradable Au NPs were clustered via acid-cleavable linkers to pinpoint mildly acidic tumor tissue [28, 30].
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