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NR1H4 is activated by intracellular bile acids and, in response, regulates expression of a number of bile acid responsive genes, mainly in liver and intestinal cells [ 31].
Abscisic acid responsive elements.
We take as an example recent published reports on microarray experiments that were designed to identify retinoic acid responsive genes.
Indeed, Prep1.2 responds to RA through a 3'-RARE (Retinoic Acid Responsive Element) located in the first intron [15].
Thiobarbituric acid responsive substances (TBARS) are routinely used to assess oxidative stress damage to membrane lipids in diverse organisms [26], [27].
PML-RARα acts as a transcriptional repressor to block retinoic acid responsive genes in the absence of ligand due to its interaction with HDACs [28].
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We unexpectedly found an elevation in skin retinol and retinoic acid levels as well as a marked elevation in retinoic-acid responsive genes due to skin Scd1 deficiency.
This letter reports a new double hydrophilic block copolymer (Scheme 1) whose microphase separation can be tuned responsively by the protonation/deprotonation of its acid-responsive block.
Moreover, it is known that this gene is co-regulated by the weak acid-responsive transcription factors Haa1 and Rim101 in response to acetic acid stress [ 6].
In addition, ethylene response transcription factor 4 (ERF4), a negative regulator of jasmonic acid-responsive defence related genes [ 28] was clearly down-regulated in these plants.
As shown in TEM images (Fig. 3a, b), acid-responsive Au NCs rapidly disassembled at pH 5.0.
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