Thus, without new, innovative funding mechanisms in place and implicit GCC support to form those alliances, and alternatives to fund projects serving marginalized populations in low-income countries with few viable markets, many of the Phase I GCC-funded ideas have very little chance to reach commercialization despite achieving proof-of-concept.
An appraisal of the product demonstrates that it achieves proof of concept; it can be highly prefabricated and enhanced occupant comfort and carbon emissions targets can be met.
To achieve proof of concept requires emotional and professional investment in the idea, institutional or collegial support, funding, commitment of time and energy, and the willingness to tolerate the risk of failure.
Both of these strategies have achieved "proof of concept status," meaning there's good scientific evidence that they work.[5-7] We continue searching for a vaccine to prevent the virus and a cure for those who already have it.
In some cases, it may be possible to start with an autologous approach to achieve proof of concept that the cell therapy has a clinical effect.
To achieve this, proof of concept studies are being undertaken at key Chinese universities and research centres to assess the relevance and transferability of Queen's University-developed technologies.
Using these optimal hot embossing parameters together with improvements in epoxy mold fabrication and a streamlined milling procedure, a production rate of ∼50 devices per week was achieved during a proof-of-concept medium volume production run.
Following the anticipated mode of action of the individualised vaccines, the induction of functional mutation-specific T-cell responses, as well as their trafficking to the tumour as determined by functional immunological readouts, and TCR repertoire profiling are straightforward strategies to achieve the clinical proof-of-concept first in human trials.
Proof-of concept experimental results are provided.
What has been achieved, though, is the important proof-of-concept that further exploring a model like PSM can be worthwhile.
Beyond the proof-of-concept results achieved, a number of future improvements are also outlined.
