Since it has been shown by Kobayashi et al. [33] and more recently by Ovanesyan et al. [34] that the zeta potential is dependent on the particle size; it could also be used to determine what particle size is optimal in combination with a certain accelerator to achieve aggregation.
In other words, even a short polyQ stretch in isolation would be subject to irreversible aggregation, whereas a much longer polyQ stretch would be required to achieve aggregation of normal sized proteins.
To confirm that exonucleolytic digestion of Exo III is absolutely necessary to achieve aggregation of AuNPs, we performed a control experiment in which we substituted Exo III with human apurinic/apyrimidinic endonuclease 1 (APE 1).
In addition to the HEK293 cell lines, transient transfection of Flag-TDP-12xQ/N and of a Myc-tagged WT TDP-43 in differentiated motor neuron-like NSC-34 cells was also able to achieve aggregation and nuclear clearance.
Consequently, a bacterial population achieves higher aggregation performance toward the chemoattractant by switching its behavior depending on the chemoattractant concentration.
We showed that by complementing self-repelling random walks with a single step push phase, our protocol can achieve data aggregation in O(N) time and messages.
Today it is achieved through aggregation of numerous individual energy loads, and hence stochastic behaviour costs are distributed to the entire aggregated stakeholders.
Web services are being positioned as the technological framework for achieving this aggregation in the context of cross-organizational business applications.
In order to assess the quality of the published studies and to consequently achieve an aggregation to the ones meeting the requirements of good scientific practice, the DaNa expert team developed the so-called Literature Criteria Checklist.
For a simple aggregate query on one table, like SELECT op (expression) FROM table WHERE predicate, it's easy to achieve online aggregation by continuously sampling from the target table.
