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Based on the high-quality training data set, the Random Forests classifier achieved specificity as high as of 0.97 and a sensitivity of 0.64 for conditional exon prediction from intron regions.
> Figure 3 (left and middle panels) shows the achieved specificity and sensitivity for all defined feature sets.
Using this strategy, we achieved specificity and sensitivity values comparable to those reported by Legendre and Gautheret, even though we scanned sequences that were three times longer.
This goal was achieved (specificity of 93.6%), and a good sensitivity (88.5%) for CV was maintained, with a good precision for both.
The described high level of achieved specificity and sensitivity demonstrates the potential and suitability of NASBA-microarray technology for the purpose of pathogen detection in microbial diagnostics or more complex analysis of microbial taxa in environment.
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As for the interaction topologies, the mode of binding and the way to achieve specificity are often specific for each family.
The ensemble pictures of these RNAs suggest that some of the unique conformations can be selected for structure-specific targeting by novel drug molecules to achieve specificity.
To achieve specificity of modification, the "clickable" handle can be genetically encoded into specific ECM proteins.
An alternative way to achieve specificity is to use mixtures of compounds and to vary the relative proportions of the components.
But although MGM Grand's "Nut," which opened a three-night run at the Kitchen on Wednesday, possesses the requisite impenetrability, it never achieves specificity.
Here, we demonstrate how achieving specificity can be aided by targeting differences in the dynamics of proteins.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com