The phrase "achieved an affinity" is correct and usable in written English.
It can be used when describing the process of developing a strong connection or relationship with someone or something.
Example: "Through years of collaboration, the two organizations achieved an affinity that greatly enhanced their joint projects."
Alternatives: "developed a connection" or "established a bond."
The proposed antidote for dabigatran is the antibody aDabi-Fab that achieves an affinity for dabigatran 350 times stronger than its affinity for thrombin.
Heteroclitic peptides, that are changed at the HLA-binding motif to achieve a higher affinity between the HLA and the peptide, are potent immunogens.
The library achieved a very high overall affinity (K d = 33 ± 8 nM) against BoNT/A light chain after only one round of selection.
Cells and debris were removed from the harvested cultures by centrifugation and depth filtration to yield HCCF. Antibody purification from the HCCF samples was achieved by Protein A affinity chromatography (Prosep A or Prosep-vA High Capacity from Millipore, Billerica, MA or MabSelect SuRe from GE Healthcare, Pittsburgh, PA).
By a process involving initial screening of a set of 87 aldehydes using an oxime ligation-based strategy, we were able to achieve a several-fold affinity enhancement over one of the most potent previously known polo-like kinase 1 (Plk1) polo-box domain (PBD) bindomainnhibitors.
A first-coordination-sphere match, in which the binding ligands are three neutral His residues, is enough to achieve a modest binding affinity (Kd on the order of ∼10 6 M) and substantial catalytic activity, and only small variations are observed depending on the surrounding structure.
Proactive brand management allows the organization to have clarity on who they are and facilitates their ability to cultivate new relationships and build new partnerships to achieve an even greater impact (brand Affinity).
The most potent variant achieved 2110-fold affimprovementvementoto an equilibrium dissociation constant (Kd) of 3.45 pM with only 7 amino acid substitutions.
The covalently bound peptides, despite their "infinite" affinity for MHC, were not demonstrably more immunogenic, which suggests that once a peptide has achieved sufficient affinity for the MHC molecule, further improvements in immunogenicity will be limited first by the natural catabolism of the complex and ultimately by the recognition and cross-reactivity of the T cell.
Expression of CCTX2 was performed as described above, and purification of the protein was achieved by affinity chromatography on a Sepharose column.
