In type I PKSs, such MT domains are often employed by noniterative trans-AT and by iterative enzymes to methylate the growing polyketide chain at the α-position, whereas noniterative cis-AT enzymes achieve the same modification by using methylmalonyl-CoA in place of malonyl-CoA as extender unit [ 32, 34].
Buhler argues that the group she calls Cynic Kids "don't like the system — however, they are wary of other alternatives as well as dismissive of their ability to actually achieve the desired modifications.
Retrofit analysis of current process to achieve the optimal modifications of process included three additional heat exchangers with shells tube of two heat exchangers according to reduction in ΔTmin from 87 °F to 40 °F.
Viral vectors, due to their ability to permanently integrate in a target genome, are used to achieve the stable genetic modification of therapeutically relevant cells and their progeny.
Because a ripple-spreading algorithm is actually a bottom-up, agent-based simulation model, we can easily define problem-specific node behavior to achieve the above two modifications.
To achieve this, the modification of the solvent composition, the addition of thickeners, fillers, aggregates and calcium hydroxide-dispersion with larger particle diameter were tested.
This television series used a number of techniques to achieve the desired outcomes, including modification of dietary habits, increasing physical activity, counseling, family involvement, as well as peer and other psychosocial support services.
To achieve the inducible post-translational modification of a H3K27-MetBio in E. coli, we designed a dual expression plasmid (designated pUADE) that expresses the biosensor construct under control of the tac promoter (P tac) [ 14] and vSET under control of the araBAD promoter (PBAD) [ 15].
They argue that other types of loan modifications achieve the same goal.
At last, the results show that the parallel versions of former sequential algorithm with simple modifications achieve the speedup up to 6.6 times.
