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Due to the injection volume limitation (<1.5 mL) associated with sc administration, high protein concentration formulations at or exceeding 100 mg/mL are required to achieve the dose.
The number obtained was only approximate and was used to estimate the dilution necessary to achieve the dose required.
IV-ibuprofen was diluted with saline to 4 mg/ml and IV infused to achieve the dose of 50 mg/kg.
To achieve the dose levels of 1, 10, and 100 mg/kg with a dose volume of 5 mL/kg, PF-05280014 stock solution (22 mg/mL) was diluted in histidine/sucrose buffer.
Similar(56)
Immediate changes in dosing practices are necessary to achieve the doses recently shown to be beneficial in patients with ARF [ 1].
When the target was not achieved, the dose was adjusted.
Whilst a doubling in dose to the maximum predicted dose calculated for hu3S193 wild type was predicted and a doubling in the tumour-to-blood AUC ratios achieved, the dose needed for tumour eradication in patients is likely to be higher than that achievable with a single infusion.
As soon as symptomatic control is achieved, the dose is reduced to 1 2 mg daily.
If serum testosterone concentration is below the normal range or if the desired clinical response is not achieved, the dose may be increased from 5 g to 7.5 10 g.
It is recommended that prophylactic treatment is started as monotherapy and at a low dose, and that the dose is increased progressively to achieve the optimal dose, taking into account possible side-effects.
125I Source 2301 and IoGold required less activity per seed to achieve the same dose to the V100-PTV due to the higher dose rate and anisotrophy constants.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com