However, while our sample size may not be sufficiently large to achieve statistical significance, analysis of the causal steps in the process using regression models and the formal mediation model suggests that IGF1 methylation partially mediates the relationship between Black race and aBW [ 22, 23].
In our study, in vitro resistance to Ara-C seemed to be associated with low probability of survival, although this did not achieve statistical significance in multivariate analysis, possibly due to the limited sample size.
Children with untreated TDI were 1.2-fold (95% CI = 0.9-1.6 0.9-1.6ikely to feel "upset" and 1.2-fold (95% CI = 0.9-1.7) more likely to have "avoided smiling/laughing" than children without TDI, but these feeling did not achieve statistical significance in bivariate analysis (P > 0.05).
In the reported study, longer filter life was identified in association with larger calibre catheters, although this factor did not achieve statistical significance in the multivariate analysis.
Impaired communication, the temperamental traits of emotionality and activity and aggressive behaviour did not achieve statistical significance in the adjusted analysis.
The result of Poisson regression representing the association of number of traffic accidents with being cigarette smoker, being waterpipe smoker, DDT, gender and DM is displayed in table 3. The variables remaining in the Poisson regression model reduced to those represented in table 4 after removing DM and gender which failed to achieve statistical significance in the multivariable analysis.
The number of patients required to achieve statistical significance was determined by power analysis.
We believe that a multi-centre, international study may be needed to achieve statistical power for a sufficiently detailed analysis.
Heterogeneity among genotypes was significant (P = 0.013), but this SNP did not achieve statistical significance in the Kaplan-Meier analysis (P = 0.077).
Similar trends were seen using subgroup analysis, although the differences did not achieve statistical significance for all analyses.
