The phrase "achieve repression" is correct and usable in written English.
It can be used in contexts discussing psychological or social mechanisms where individuals or groups suppress thoughts, feelings, or memories.
Example: "In order to cope with the trauma, she had to achieve repression of her painful memories."
Alternatives: "attain suppression" or "reach denial".
To balance stress tolerance and fermentation performance, we inserted the promoter of a gluconeogenic gene, PCK1, into the 5′-untranslated 5′-untranslated of the regiongene in a laboratory strain to achieve repression of RIM15 gene expression in the glucose-rich early stage with its induction in the stressful late stage of alcoholic fermentation.
Only an NLS was added to build repressors (TFR), which therefore rely on steric hindrance to achieve repression.
Unlike other mechanisms that inhibit Gli induced gene transcription, the repressor domain identified here does not utilize Histone deacetylases (HDACs) to achieve repression, as confirmed by HDAC inhibition studies and pull-down assays.
Using these rates, we determined that with 8 nM of antisense RNA plasmid, we achieve 72% repression, which is comparable to the 85% steady-state repression level previously observed in vivo.
Ajuba is able to recruit to RAREs arginine methylase activity that in turns is essential to achieve transcriptional repression.
Mature miRNAs pair with target mRNAs with the assistance of Argonaute to achieve translational repression and/or mRNA degradation (reviewed in [ 17]).
In order to achieve sufficient repression in E. coli cells of constructs containing cellulases and cellulosomal operons driven by the thlOID promoter, we modified the pJ201 Biobrick2 vector and the pMTL-JH16 integration vector to contain the lacI Q gene.
Both c-Ski and c-SnoN achieve this repression by recruitment of the transcriptional corepressors N-CoR and mSin3 [ 91], which in turn associate with histone deacetylases, thereby leading to the formation of a repressive SMAD complex on the target promoter.
Intuitively, by repressing the genes through a common activator such as Gal4p, the cell achieves the repression in a coordinated fashion, instead of repressing each gene through an independent URS.
Recently, we have shown that inhibition of HSV and HIV replication can be achieved by repression of HSV and HIV genes in their host cells, with tailor-made ZF TFs [17], [18].
We therefore transiently transfected HGF and NK4 constructs together and achieved a repression of HGF signaling.
