Sentence examples for achieve maximal efficacy from inspiring English sources

Tenocytes represent a valuable source of cells for the purposes of tendon tissue engineering and regenerative medicine and as such, should possess a high degree of tenogenic differentiation prior to their use in vivo in order to achieve maximal efficacy.

69 A significant disadvantage to the clinical use of raltegravir is the requirement for twice-daily dosing to achieve maximal efficacy.

There are many peripheral pathways that can affect mitochondrial metabolism, nutrient absorption, vagal feedback pathway or lipolysis, and nutrient absorption or the vagal feedback pathway, such that these peripherally acting agents can potentially be combined with CNS agents to achieve maximal efficacy.

This can be potentially translated into targeted cellular and tissue-specific clinical applications designed to achieve maximal therapeutic efficacy with minimal side effects.

Can we improve an individual's microbiota to achieve maximal therapeutic efficacy of immunotherapy?

These data encourage the development of vaccine technologies that can induce strong antibody and T cell responses against multistage malaria antigens in order to achieve maximal protective efficacy.

Development of drug combination therapies for cancer can lead to more effective therapies to overcome drug resistance and achieve maximal drug efficacy.

Identifying such genes, and defining the protein product threshold below which their associated compensatory pathways are activated, could help to define the precise inhibitor dosage to achieve maximal therapeutic efficacy.

To achieve maximal clinical efficacy we found the most common number of titrations was 2 with an increasing proportion of patients on 37.5 and 50 mg dosages during the time-course of the study.

Selective inactivation of multiple kinases is not an undesirable pharmaceutical profile for a small molecule inhibitor and, in fact, could be the best strategy to achieve maximal clinical efficacy of an anti-cancer agent [ 38].

We conclude that donors self-regulate their analgesic usage to achieve maximal relief and that incomplete relief with acetaminophen plus codeine may be due to limited efficacy of this analgesic preparation.