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Indeed, because selective modulation of P-gp in cancer cells (and not at physiologic sites) will be difficult to achieve, attempts to circumvent MDR will need to consider the profound effects on the pharmacokinetics and distribution of concomitantly administered drugs.
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Currently, midwives at this hospital providing continuity of care to women eligible for a VBAC are achieving attempt rates of 62.5% and success rates of 76%.
They are all biomaterials conceived and prepared in situ, a procedure which follows a kind of Occam's razor: making biological engineering simple can be best achieved attempting to keep it simple [ 21] by applying nature's original technology.
If we fail to achieve or attempt to achieve cultural harmonization then economic globalization will create unimaginable conflicts.
She paused to enjoy the moment she had worked so hard to achieve, then attempted to pull open the heavy iron door.
Financial and social supports from local governments would be helpful for FCs to achieve this attempt.
For this target, the novel laminated CuO/ZnO p n heterostructured systems are introduced to achieve this attempt.
Verbal encouragement was given during the attempts to achieve maximal effort.
Vigorous verbal encouragement was given in an attempt to achieve maximal effort level.
Davros, realising that his creations have achieved sentience, attempts to destroy the bunker, but he is shot by a Dalek.
Taken together, these could swamp any savings achieved by attempts to reduce misuse, abuse or fraud or increase efficiency in the medical care delivery system.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com