By covering an obstacle with combined connected patches, cloaking effect can be achieved at multiple frequencies so as to expand the operating band.
In the case of the SCL dataset the possible best clustering performance is achieved at multiple values of the similarity threshold therefore no single t γ and the corresponding vertical line is indicated on the graph (see: Additional file 17: Fig. S13).
Therapeutic intervention could be potentially achieved at multiple levels, for example, by (i) targeting NOX4 directly using specific inhibitors, (ii) indirectly inhibiting NOX4 using antioxidants or Se to scavenge ROS/H2O2, (iii) enhancing NO signaling via NO-donors, stimulators/activators of sGC, and/or (iv) preventing cGMP degradation using PDE inhibitors.
If no exits can be achieved at enormous multiples because the system will not pay for these multibillion-dollar drug franchises, then early-stage investors will have much less incentive to participate in very high risk bets.
With regard to the achieved impact at multiple governance levels – as described below (Table 2), the national and regional platforms can be seen as a key success factor for the broad implementation of the ManuFuture Road across Europe.
During this stage, students have multiple attempts to achieve at least 80%, and once this is achieved they are given access to the second stage of the test.
Pretreatment has multiple objectives that are challenging to achieve at once.
Each genomic region was verified by sequencing multiple independent clones in order to achieve at least 5× coverage/nucleotide.
Even so, British Columbia has shown the rest of Canada, a country with high carbon emissions per head, that a carbon tax can achieve multiple benefits at minimal cost.
As a result, it is difficult to achieve multiple objectives at the same time.
