The phrase "achieve activity in" is not correct and does not convey a clear meaning in written English.
It may be intended to express the idea of successfully engaging in or completing an activity, but the wording is awkward and unclear.
Example: "We need to find ways to achieve activity in our community programs to increase participation."
Alternatives: "engage in" or "participate in".
In vivo experiments utilizing Cre variants also often require in vitro characterization and some applications involve transfection of purified enzyme to achieve transient activity in the cell.
In addition, to achieve high activity in heterogeneous catalysts, composite nanoparticles are the logical strategy because of a large surface to volume ratio, thus increasing catalytic activity.
Three doses of LAMB at 5 mg/kg/day in rabbits were required to achieve fungicidal activity in cerebrospinal fluid (cumulative area under the concentration-time curve, 2,500 mg · h/liter).
For example, by using an inhibitor targeted to a Poly(ADP-Ribose) Polymerase (PARP) that is synthetically lethal to a cancer-specific mutation (BRCA), researchers could target cancer cells to achieve antitumor activity in tumors with the BRCA mutation[11].
Preliminary data in advanced pancreatic cancer (Tempero et al, 1999) led us to hypothesise that gemcitabine administered at FDR may achieve higher activity in HCC.
In this respect, our tentative identification of a thioredoxin and a minor Lhcb species in immunoprecipitates prepared with antibodies against CAO suggests possible avenues to achieve catalytic activity in vitro.
Aspirin, a widely used anti-thrombotic drug, achieved comparable activity in this model system at a dosage of ca. 110 μmol/kg.
GEFs render Rac1 capable of associating with the Nox1/p22phox complex, which is another indispensable step for achieving enzymatic activity in Nox1 [ 35].
Titanium thin films have been designed to achieve efficient photocatalytic activity in the visible range.
Consistent with limited clinical data, a minimum %T > MIC of 40%to50%0% would be suggested to achieve in vivo activity in otitis media, with maximal activity at approximately 70%T > MIC.
