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Based on the two-tailed Student's t test with the assumptions of equal standard deviation in the control and treatment/disease groups, and unpaired data analysis if different animals are used for each group, the goal is to calculate the number of animals to achieve a significant difference (P < 0.05) between the control and treatment/disease groups [37, 38].
Aspirin failed to achieve a significant difference in the composite cardiovascular end point.
At the end of each day period, haemoglobin values increased to achieve a significant difference as compared with baseline.
This, together with the small sample size, made it difficult to achieve a significant difference compared to those subjects in the normal range of HbA1c.
An a priori power analysis showed that twenty subjects were required to achieve a significant difference in EMG with an alpha level of 0.05 and 80% power; accordingly 22 were recruited to allow for data loss.
Power calculations suggested that 58 patients per group would be needed to achieve a significant difference in the incidences of delirium but the current study only included 25 patients per group.
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Thus, our study had a greater reach, achieved a significant difference in provider behavior, but was not able to demonstrate an impact on dental patient behavior.
The main objective of this study is to determine whether placement of the electrode below the recommended location achieves a significant difference in the calculation of the DeMeester score.
In many cases for TS genes, the data seem too sparse to achieve a significant statistical difference.
The primary end-point, change from baseline to week 12, was not achieved although a significant difference favouring rasagiline was observed at 4 weeks.
The response was achieved rapidly: a significant difference in ACR20 response rate between treatment groups was evident at week 2, and the difference remained significant throughout the study (p<0.005) (figure 2A).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com