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Many Tc variants have been produced, both to overcome bacterial resistance and to achieve a broad range of binding strengths.
By assessing the specific regions for mRNA folding, we could construct a predictive design method, UTR Designer, and demonstrate that proper codon optimization around the 5′-proximal coding sequence is necessary to achieve a broad range of expression levels.
There is no 'one size-fits-all' monitoring well, but there is a tool-box or ensemble of solutions that can achieve a broad range of relevant monitoring objectives given constraints of site characteristics and budgetary limitations.
This remarkable increase in flexibility to achieve a broad range of product qualities is the result of the ability to control the rate at which individual crystallization tasks are executed as well as the material flows between those tasks.
A number of strictly euthymic patients were systematically looked for, to achieve a broad range of patients' composition (i.e., those with a HAMD-21 ≤ 3, based on practice in a recent study regarding subthreshold symptoms in bipolar disorder) (Bonnin et al. 2012).
Forty former ICU patients were recruited throughout the UK, using maximum variation sampling, to achieve a broad range of experiences of intensive care.
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This approach can thus expand the usefulness of these two polymers and achieve a broader range of DNA release profiles without the need to synthesize polymers with new structures or properties.
The method enables achieving a broad range of continuous spectral distributions and compares favorably with other methods proposed in the literature.
The fact that after denervation the solely pressure driven control of frequency only generates a much smaller frequency range confirms that control of labial tension through the neuromuscular system is an important aspect of achieving a broader range of acoustic features [27].
This reduced the bias associated with patients nominating members of their social network and probably achieved a broader range of respondents.
These experiments first demonstrated that a robust SEAP signal was detectable under conditions of dual drug induction over a range of plasmid concentrations and allowed to determine the optimal plasmid concentrations to achieve a broad dynamic range between the induced and uninduced conditions (see legend, Figure 2).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com