To maximize the average achievable rate, user needs to solve the following optimization problem, as mentioned in (4) (22).
The relationship between heavy atom counts and best achievable RMSDs was also examined on the very same conformer set as mentioned above (OPLS3, water, 5 kcal/mol energy window).
As mentioned earlier, the rate region is the set of all achievable points.
In practice, these suppression numbers are easily achievable by using a combination of passive suppression and active analog suppression, but as mentioned earlier, in our experiments, no active analog cancellation is performed to keep all signal components accessible.
As mentioned above, there is a trade-off between the complexity and the achievable rate, which means we have to sacrifice the optimality of the solution when reducing the complexity.
As mentioned before, the conventional outage probability has a larger diversity order than what is achievable, while the tighter lower bound only achieves a diversity order of two.
However, the detection of low abundance proteins in complex samples requires measurements of high sensitivity and large dynamic range, aspects of MS performance that are currently achievable and presently being greatly improved due to developments in MS-based instruments and new separation technologies, as mentioned earlier.
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