The phrase "ach contributed to the" is not correct in English.
Did you mean "has contributed to the"? You can use the corrected phrase when discussing someone's or something's role in a particular outcome or achievement.
Example: "Her research has contributed to the advancement of renewable energy technologies."
Alternatives: "has played a role in the" or "has aided in the".
Previous work suggests that a loss of subcortical dopamine (DA) and/or acetylcholine (ACh) contribute to the pathophysiology of dementia in PD.
If ACh contributes to attentional modulation, then attention should reduce spatial integration at the perceptual and neuronal level.
Modulation of visual responses in the primary visual area (V1) by acetylcholine (ACh) contributes to visual attention [1] and learning [2].
Future work on the mechanisms of attention might focus on delineating whether ACh contributes to changes in cortical synchrony during states of attention in addition to its contribution to firing rate changes (Herrero et al., 2008).
Acetylcholine (ACh) contributes to learning processes by modulating cortical plasticity in terms of intensity of neuronal activity and selectivity properties of cortical neurons.
It is known that monoamine and ACh contribute to flexible behaviors mainly via prefrontal modulation.
Despite this wealth of data, it is unclear how ACh contributes to neuronal processing during selective attention.
It is thus tempting to speculate that ACh contributes to increased gamma oscillations as seen during selective attention in V4 (Fries et al., 2001) in addition to the proposed balanced NMDA AMPA activation ratio (Buehlmann & Deco, 2008).
Because this behavioral phenotype reminiscent of PDD has been reproduced in the DA-depleted CHTHET mouse based on known neuropathological features of PDD (i.e. loss of DA in the basal ganglia combined with loss of ACh), our data suggest that both loss of DA and ACh contribute to dementia in PDD.
Hence, we postulated that leukocytic ACh contributes to the pathogenesis of CAI.
