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The employment of molecular knowledge needs appropriate experimental design and accurate phenotyping.
Wide-scale use of root- related genetic information in breeding programs relies on accurate phenotyping of relatively large mapping populations.
Nonetheless, efficient and accurate phenotyping, modelling and collaboration with breeders remain important challenges, particularly when defining ideal RSA for different crops and target environments.
Fine mapping of root QTLs is complicated by the high plasticity of root development, which, in turn, necessitates accurate phenotyping using a large mapping population.
The integration of accurate phenotyping and the selection of the best class representing the genetic variability of the whole population in early generations are critical steps for the practical implementation of this ultimate novel breeding strategy.
As costs of genotyping continue to drop, accurate phenotyping is emerging as the rate-limiting step for conducting genomic studies.
Similar(27)
Furthermore, we find that iFBA predicts different and more accurate phenotypes than the ODE model for 85 of 334 single gene perturbation simulations, as well for the wild-type simulations.
While the biomedical literature contains broad coverage of specific phenotype algorithm implementations, no work to date has attempted to generalize common approaches into design patterns, which may then be distributed to the informatics community to efficiently develop more accurate phenotype algorithms.
Lee et al. [11] identified condition-responsive genes, whose combined expression measurements can be used to perform accurate phenotype classification.
The first challenge was to define an accurate phenotype definition.
Central to the study of complex phenotypes are accurate phenotype definitions.
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