For the development of rapid triage tests, non-sputum based tests for active TB, highly predictive LTBI tests, and an accurate test for cure, we need validated biomarkers.
The potential for surgical cure necessitates accurate localisation, ideally using a combination of CT, MRI and EUS, often together with SSRS and, in some centres, DSA with intra-arterial calcium stimulation.
However, the development of new TB regimens is hindered by the limitations in our understanding and use of preclinical models; the paucity of accurate, early surrogate markers of cure, and challenges in untangling the individual contributions of drugs to multidrug regimens in a complex, multi-compartment disease.
qPCR after immunosuppression has until now been the most accurate technique for defining parasitological cure in T. cruzi infections (20, 28, 29).
"IDSA claims the test is accurate and most patients are cured with 2-4 weeks of antibiotics," reads a statement by the Patient-Centered Care Advocacy Group.
Why aren't more doctors lobbying for a completely accurate test and a truly effective cure? A. J. BLYSKAL Danbury, Conn.
The lack of accurate early post-treatment tests of cure prevents appropriate patients information and councelling.
Thus, we can conclude based on the figures in Table 6 that the OLLLNcr model gives a more accurate estimate for the proportion of cured individuals.
Results show that the developed calorimeter is a simple, inexpensive and reasonably accurate technique for monitoring the EB curing of cationic epoxies.
For a more accurate characterization of the activated and/or cured PU coatings, pure polyisocyanate resins and pure co-reactants involved in the preparation of certain systems were analyzed individually by Py-GC/MS in the same fashion.
