Exact(6)
Only 11 studies were included in this diagnostic test accuracy review.
Thus far, PHSKC has reviewed 46 charts from 8 hospitals to validate system accuracy; review of data from the remaining hospital is pending.
In situations where the prior prevalence of LVSD is 30%, a figure that matches the median prevalence in the included studies in this diagnostic accuracy review, a negative ECG or BNP lowers the post-test probability of LVSD to 10%.
In this Cochrane systematic diagnostic test accuracy review some subgroup analyses were not possible, because studies did not report the data in sufficient detail to assign all patients to subgroups.
Our results are more consistent with a recent diagnostic accuracy review of cohort studies that included patients in both primary and secondary care presenting with 'alarm' features (Ford et al, 2008).
Of the 71 trials of HRP-2 RDTs included in the Cochrane diagnostic test accuracy review, 51 were conducted in areas of lower endemicity with a pooled sensitivity of 95.1% (95% CI 93.1 to 96.6) and specificity of 95.9%9595% CI 94.1 to 97.2) (Abba 2011).
Similar(54)
Reviewers and readers of test accuracy reviews need to check that the results or limitations of quality assessment are incorporated in the abstract and conclusion of the review.
Its use in Cochrane diagnostic test accuracy reviews is new.
The methodological quality of all individual study was assessed using the QUADAS-2 tool [16], which was recommended by the Cochrane handbook for diagnostic test accuracy reviews.
We also used the information on cut-off from each study to determine an optimal cut-off by maximizing the Youden index (sensitivity + specificity-1) in this diagnostic test accuracy reviews.
CM will participate in performing several test accuracy reviews.
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