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Exact(12)
Here, we exemplify the power of combining database presence with MS/MS similarity boosting in order to improve the accuracy of structure annotations from mass spectra, an approach which was successfully implemented previously [20].
Another way to improve the accuracy of structure prediction is to incorporate experimental data to the secondary structure prediction modeling (Mathews et al. 2004; Deigan et al. 2009; Low and Weeks 2010; Kladwang et al. 2011; Hajdin et al. 2013; Leonard et al. 2013).
Since protein folds are classified into superfamilies based on common functions and evolutionary relationships, it is likely that the PCAIN-based methodology enables handpicking of an optimal functionally-related template molecule for modeling the structure of the unknown protein, thus contributing significantly towards improving the accuracy of structure prediction.
We therefore needed to study the impact of the accuracy of structure prediction.
A scoring function (C-score) associated with I-TASSER modestimatesaccuracyuracy of structure predictions.
This showed that RScan was greatly limited by the accuracy of structure prediction.
Similar(48)
The accuracy of structure-based prediction methods is usually higher, but they can't be used in high throughput annotation, as it requires the high-resolution 3D structure of the query sequence.
Although the results are case-based they have broader implications on both prediction accuracy of structure-based TF binding affinity predictions and interpretation of biological functions due to binding affinity differences.
The modelling accuracy of structures depends on the underlying lattice (e.g. 3D cubic or 3D face-centered-cubic (FCC) and the number of monomers per amino acid.
The feasibility of the present study has been facilitated by the recent progresses of the crystallographic techniques, which have increased the number and the accuracy of structures of these nonglobular systems.
With the 2D structure as constraint, the accuracy of 3D structure prediction can be significantly improved.
Related(19)
adequacy of structure
regularity of structure
reliability of structure
clarity of structure
authenticity of structure
accuracy of configuration
accuracy of articulation
accuracy of frame
accuracy of structures
accuracy of drug
accuracy of prediction
accuracy of nursing
accuracy of crime
accuracy of perception
accuracy of packet
accuracy of cinema
accuracy of congestion
accuracy of polling
accuracy of climate
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