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Because AKI cases are not frequently biopsied, the diagnostic accuracy of concentrations of Scr and urinary biomarkers for histologic acute tubular injury is unknown.
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A newly developed experimental method using redundant measurements and a Data Reconciliation procedure improved the accuracy of concentration profiles for the gas and the liquid phase.
One of them was equipped with a non-dispersive infrared (NDIR) CO2 analyzer LICOR-820, with a measurement range of 0 to 2,000 ppmV, an accuracy of concentration reading of 2% and a repeatability of ±5%.
Specifically, the improvement in the accuracy of concentration estimates that can be obtained using the 5PL over the 4PL as a function of the asymmetry present in the data is studied.
The combination of system magnification and flow-cell depth determines the accuracy of concentration measurement.
As in the case of PG, fragmentation affects the accuracy of concentration measurements significantly.
Theoretically, the experimental uncertainty of CR for a given accuracy of concentration measurements depends on the percent reduction in particle concentration (100×P) from inlet to outlet of the ideal 'chamber geomety'.
Our work showed that the accuracy of concentration measurements based on fluorescent dyes and qPCR is influenced by the degree of DNA fragmentation, while this effect was not observed in DNA quantification by spectrophotometry.
Considering possible acceptance criteria for scanners acquiring data in a clinical trial setting, an achievable accuracy of concentration measures in large uniform regions of activity of 10%% (average) over a range of clinically realistic true concentrations (50 – 300 kBq/ml) may be considered suitable performance.
For the SS method, CR/Fl = 1/(1−P) − 1 according to eqn 2, leading to (5) For a given accuracy of concentration measurements the relative uncertainty, (δCR/CR)/(δ C/ C i), versus percent reduction of measured concentration (i.e. percent particles cleared), 100×P, from Eqs. (4) and (5) is shown in Fig. 3 for the FTC and the SS methods.
FLUENT gives a mixed image in terms of accuracy of predicted concentrations compared to the wind tunnel experiment.
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