Apparently, the greater the number of uORFs contained in the 5'UTR, the greater the inhibitory effects on translation, suggesting an accumulative effect on the overall level of translational efficiency [ 12].
The accumulative issue took on greater importance in the late 1980s and early 1990s as a growing list of prominent players (Al Toon, Merrill Hoge, Troy Aikman, and Steve Young) retired from the game because of 'post-concussion syndrome' [ 16, 17].
While stabilization energy differential on hydrogen bonds is likely to be small for individual residues, the accumulative effect on multiple hydrogen bonds may have a dramatic impact on ligand affinity.
"I'm quite convinced that the more times we attack, there will be accumulative pressure on the [Syrian] regime to react," Shlomo Bron, a senior Israeli security figure, said.
Moreover, MPK treatment also had an accumulative effect on soil OM.
Thus, the increase of iterative rounds might exhibit an accumulative effect on TGase production of the mutants.
The Dolgaya spit is the large accumulative bodies on the Russian coast of the Sea of Azov.
To investigate the accumulative effect on TGase production by iterative ARTP mutagenesis, the mutation and screening results for each round were collected and compared.
Data of accumulative adsorption on molecularly imprinted polymers from the continuous loading experiment suggests that there are two different kinds of recognition sites in molecularly imprinted polymers.
Although a minor splicing functional defect can be tolerated by mice which have a shorter life span, it may render an accumulative effect on retinal degeneration in humans.
