Sentence examples for accumulation phenotype from inspiring English sources
aeruginosa) phenotype of epa-18 mutants that is easier to track than the enhanced pathogen accumulation phenotype when the COPAS Biosort system is not used.
Fifth, elevated levels of DLK-1, a MAPKKK upstream of PMK-3, result in a GLR-1 accumulation phenotype similar to that of rpm-1 mutants.
Since ARF6 activation is coupled to the efflux of recycling endosomal membrane [10], we examined the impact of constitutive ARF6 activation on the lipid accumulation phenotype induced by U18666A.
Notably, simultaneously depleting either two of Dhc62B, Dlc90F or p25 shifted the misdistribution from the peduncle to the lobes (e.g. Figures 3H and 3I), better recapitulating the terminal accumulation phenotype in other dynein/dynactin mutants.
Rab proteins are general regulators of membrane traffic and have been of particular interest in NPC-disease, as overexpression of several Rabs appears to reverse the cholesterol accumulation phenotype in cell culture [reviewed in 52].
We arrived at the study of membrane traffic in adipocytes through a Collagen IV accumulation phenotype.
Based on their anthocyanin accumulation phenotypes, we selected 20 transgenic lines for further characterization.
We took advantage of previous observations that starvation induces an accumulation of lipid droplets in larval oenocytes [13], and consequently, we examined whether oenocytes from animals with reduced AMPK would show aberrant oenocyte lipid accumulation phenotypes.
Lastly, oenocytes are thought to be involved in the processing of fats making them ready for utilization [13], suggesting that the accumulation phenotypes seen here may be linked to the observed lower global triglyceride levels.
In two larger studies, one demonstrated a significant association of the FAAH P129T genotype variant with overweight and obesity [28] and one study showed no significant association of this variant with fat accumulation phenotypes [32].
Demonstrations of increased hyperactive locomotor responses, lower triglyceride levels, increased hunger-driven feeding behaviors, higher metabolic rates, and lipid accumulation phenotypes in liver-like oenocytes indicate that the loss of AMPK leads to a persistent starvation signal both at the organismal and cellular levels.
