Sentence examples similar to accumulation of unprocessed applications from inspiring English sources

Consistently, METTL3 depletion reduced the binding of DGCR8 to pri-miRNAs and led to reduction of mature miRNAs and accumulation of unprocessed pri-miRNAs.

The results were in line with the previous speculation that accumulation of unprocessed precursor proteins in the cytoplasmic membrane was detrimental, and supported the idea that cell death was caused by some unusual tie-up of Pre-Exg with the SecYEG translocation machinery, thus imposing an inhibitory effect on the secretion of endogenous secretory proteins.

Proteasome inhibition by bortezomib ultimately results in UPR-mediated apoptosis due to the accumulation of unprocessed and misfolded proteins.

The resulting accumulation of unprocessed or partly processed GAGs dermatan sulphate, heparan sulphate, keratan sulphate and chondroitin sulphate in lysosomes causes progressive damage of affected tissues, including heart, respiratory system, bones, joints and central nervous system [1].

Accumulation of unprocessed inhibin α-subunit in the media suggested that this inhibitor affects cleavage but not secretion.

This led to the accumulation of unprocessed profurin, as indicated by the increased intensity of the 103kD band (Fig. 4C, lower panel).

The lower translation rate is believed to decrease protein load on the secretory system, reducing the accumulation of unprocessed products in the cytoplasm.

This led to accumulation of unprocessed SREBP-1.

Our quantitative PCR analysis confirmed accumulation of unprocessed RNAs in these parasites.

Accumulation of unprocessed untranslocated forms of the proteins Kar2, PDI, and Gas1 were detected by western blotting.

Prelamin A staining can be used as a marker for abnormal accumulation of unprocessed lamin A at the nuclear lamina.