The phrase "accumulation of toxic" is correct and usable in written English.
It can be used in contexts discussing the buildup of harmful substances or effects, often in environmental or health-related discussions.
Example: "The accumulation of toxic waste in the river has raised serious concerns among environmentalists."
Alternatives: "build-up of harmful" or "gathering of toxic".
Therefore, we wondered whether the synergistic toxicity of chlorpromazine and BAs could be explained by chlorpromazine-induced accumulation of toxic BAs, which subsequently modulate death receptor signalling.
Ferroptosis is a nonapoptotic form of cell death characterized by the iron-dependent accumulation of toxic lipid reactive oxygen species.
The characteristics of old age, such as wrinkles, hearing loss or cancer, are actually due to falling autophagy levels and the accumulation of toxic wastes in the cells".
Accumulation of toxic trace elements generated by coal-fired power stations presents a serious threat to the environment.
Drug-induced cholestasis (DIC) is primarily associated with impaired bile acid (BA) homeostasis, leading to the intrahepatic retention and accumulation of toxic BAs5.
Additionally, a deacylase FlsH was identified which may help to prevent accumulation of toxic quinone methides by catalyzing hydrolysis of the acyl group.
In LOAD, accumulation of toxic Aβ and p-tau may not be the initial cause of neural degeneration and may instead be consequences of other causative factors5,6.
The response leads to a decrease in cytosolic protein synthesis and increased proteasomal activity to reduce the accumulation of toxic mistargeted proteins.
However, other factors such as smoking may influence the metabolism and thereby the accumulation of toxic substances.
The inhibition was thus mainly due to the accumulation of toxic Zn II) ions in anammox biomass.
Submerged macrophyte used in simulated wetlands showed a significant time dependent accumulation of toxic metals (p ≤ 0.05).
