The phrase "accumulation of the changes" is correct and usable in written English.
It can be used when discussing the gathering or collection of modifications or alterations over time.
Example: "The accumulation of the changes in the policy has led to significant improvements in employee satisfaction."
Alternatives: "collection of the changes" or "gathering of the changes".
But it made it plausible to assume that neutral mutation processes under genetic drift played a major role in the accumulation of the genetic changes which distinguish the Neanderthal and modern human mtDNAs.
Furthermore, by lowering their chances of transmission, genetic drift has the potential to prevent the accumulation of advantageous changes at the population level, thereby impeding the long-term adaptation of HIV-1 [ 31].
This variation is a reflection of the accumulation of subtle changes through the span of evolutionary time that has elapsed since species diverged from their common ancestors.
This suggests that when measuring individual branches the deviation from the mtDNA rate is small enough not to be significant with the tests we used (ANOVA comparisons and the null distribution of the K-scores), but when measured over the whole tree with patristic distances the accumulation of changes in the body morphospace is decoupled from the amount of mtDNA change.
Together these data support the hypothesis presented in Fig. 1 that the age-related accumulation of AGEs changes the properties of articular cartilage and thereby renders the tissue more prone to the development of OA.
It is conceivable that the same vtx2-phage has been acquired in two different events and that the selective pressure impeded the accumulation of changes in the phage sequence before the phage infection events occurred.
Thus, the sum βN + βNG captures the variability on the accumulation of nonsynonymous changes per gene or the proportion of nonsynonymous polymorphic changes that are nonlethal in a given gene (Eilertson et al. 2012 ).
The molecular clock concept is based on an assumed regularity in the accumulation of tiny changes in the genetic codes of humans and other organisms.
Common diseases increase with aging, which is related to the accumulation of epigenetic changes through the lifetime of an individual.
The overall wing pattern evolved through the accumulation of changes from the most ancestral wing pattern at node A. Then, at node C, the Cd in the forewing changed to a single broken line (Ch 3), the B in the hindwing was vestigial (Ch 7), and the Cp element in the hindwing became fragmented (Ch 8).
