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To exemplify this point it was observed in congenic bone marrow transplants that there was a 2 to 3 fold accumulation of recipient and donor NKPs, in tumor-bearing mice compared to control mice.
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This suggested that the introgression has strongly influenced the ion accumulation of the recipient rice under the salt stress condition (Figures 3 and 4), and escalated the injuries of Na+ and Cl- in shoots.
According to this study, accumulation of exosomal miRNAs in recipient cells is necessary for miRNA-based communication.
Comparison of liver sections revealed that there was a strong association of lipid accumulation with recipient group (Fig. 8A), similar to the observation of macrophage recruitment.
We also found intermediate situations where the SNP distribution clearly suggested recombination events that were more ancient and likely followed by accumulation of a few mutations in the recipient or the donor strains (Supplementary Fig. 7a).
Interestingly, adoptive transfer of wild-type neutrophils to 5-lipoxygenase-deficient mice restored arthritis development and the accumulation of neutrophils (including 5-lipoxygenase-deficient recipient cells) at the site of inflammation indicating an important role for neutrophil-derived LTB4 in feedback amplification of neutrophil recruitment.
Injection of syngeneic BM-DCs loaded with OVA and α-GalCer resulted in priming of OT-II cells in C57BL/6j and untreated lang-DTREGFP recipients, with enhanced accumulation of OT-II cells in the blood at day 7 compared to non-vaccinated mice (Fig. 3A).
Rather, it may reflect defective lipogenesis in adipocytes, as suggested by the reduced lipid accumulation of p66Shc-/ adipocytes transplanted into WT recipient mice [ 17].
Transplant arteriosclerosis is characterized by inflammation and intimal thickening caused by accumulation of smooth muscle cells (SMCs) both from donor and recipient.
We hypothesize that accumulation of MPs during storage induces a proinflammatory state in the recipient.
We also found that the reversion rate of these putative CTL escape mutations upon transmission to HLA-unmatched recipients varies considerably, suggesting that the rate of accumulation of CTL escape mutations in a given population differs substantially between mutations.
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