Increased hillslope erosion following land clearance has instigated the accumulation of post-settlement alluvium (PSA), which has altered the boundary conditions and bank materials within which streams flow.
Consequently, it was suggested that this enhancement is due to the accumulation of post-flare loops suppressing the pre-existing loops.
Additionally, in comparisons with shorter target trajectories, the temporal effects differ, since accumulation of post-excitatory inhibition is activity dependent (compare figure 1 a(i) with f(i)).
In S. cerevisiae, temperature-sensitive mutations in exocyst components result in an accumulation of post-Golgi vesicles that are unable to fuse with the plasma membrane (8).
This concept is based on the view that there is a combination of effects that lead to the accumulation of post-translationally modified proteins by ROS/RNS-dependent mechanisms, which is supported by the present study.
Mutating these two positions in the leader peptide of nisin precluded the removal of the leader peptide as demonstrated by the in vivo accumulation of post-translationally modified NisA with the leader peptide still attached.
Similar to rapamycin (which is well known for its anti-aging effects) [ 7], the accumulation of post-translationally unmodified, transactivation-proficient (but not transactivation-deficient) TP53 resulted in MTOR inhibition and senescence suppression [ 6].
Alzheimer's disease is a multi-proteinopathy, involving both extracellular amyloid-β deposits (i.e. amyloid-β plaques) and intracellular accumulation of post-translationally modified tau proteins [i.e. neurofibrillary tangles (NFT ], recently reviewed by Murray et al. (2014).
Motor neurons with redistribution of GM130 staining to a restricted area of the cell body showed a similar redistribution of CGRP (Fig. 5d), but in some occasions also showed a dramatic accumulation of CGRP in the rest of the cell body (Fig. 5c), putatively representing the accumulation of post-Golgi CGRP vesicles [ 64].
Indeed, because sexual signals affect mate recognition and thus pre-mating isolation, their divergence may lead to reproductive isolation more rapidly than the accumulation of post-zygotic barriers [ 1, 2] However, the relative importance of different evolutionary forces in causing variation and divergence of sexual signals remains unclear [ 3].
Microscopy images revealed the accumulation of post-Golgi apparatus secretory vesicles (approximate size, 40 to 90 nm) and larger ovoid structures consistent with late endosomes (approximate size, 250 nm) when strain tSEC6 was grown under repressing conditions (Fig. 4B; see also Fig. S2 in the supplemental material).
