"A trend of later fatherhood will accelerate the accumulation of paternal-origin de novo mutations [genetic causes of disease] in the gene pool, gradually reducing human fitness in the long term.
The association of caloric restriction with low inflammation suggests a role of energy accumulation in the origin of the chronic inflammation.
Whereas it is well established that deletion of Nrf2 causes ROS accumulation, the origin of these ROS is unknown.
Does emigration really drain human capital accumulation in origin countries?
This suggests strong limiting effects of nutrient-poor soils on growth and biomass accumulation for all species, independent of origin [35].
This suggests strong limiting effects of nutrient-poor soils on growth and biomass accumulation for all species, independent of origin [ 35].
Finally, it remains to be seen whether the principles of origin and accumulation apply to terrestrial biodiversity, or whether these evolutionary mechanisms are restricted to high-dispersal media, the exclusive domain of the world's oceans.
Our data indicates that the Greater Caribbean is both a center of origin and accumulation for genetic lineages within species (e.g. Chromis multilineata and Halichoeres bivittatus) and for sister species within genera (e.g. Sparisoma).
The combination of this transatlantic distribution and the lack of a marked genetic break between populations in the two western Atlantic provinces (see Results) makes it a good candidate to study the roles of origin versus accumulation in explaining high species diversity in the Greater Caribbean.
In any event, the exercise-mediated reduced-abundance of nonmyogenic clones is important, since regardless of their origin, accumulation of nonmyogenic instead of myogenic cells that form the contractile units may hinder muscle functioning, maintenance and repair.
Indeed, the accumulation of points near the origin of the Euclidean distance plot shown in Figure 4A confirms this to be generally true.
