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But the frenzied accumulation of insignificant others isn't painless either.
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Membrane autopsy revealed only an insignificant accumulation of biofouling layer despite the absence of disinfection.
LC3 knockdown (KD) also resulted in an increased, although insignificant accumulation of un-degraded GJ vesicles by 32±9%9% (n = 4) (Fig. 6C).
Consistent with our hypothesis and the observed slow induction kinetics of CA9, we observed small but insignificant accumulation of 5-hmC at the CA9 TSS by 16 hr of hypoxia, accompanied by an increase of unmodified cytosine at the HRE.
Metabolite balancing is based on the assumption that accumulation of intracellular metabolites is insignificant compared to the extracellular fluxes in batch and fed-batch cultures (Niklas and Heinzle 2012).
However, the longer chain (over C12) of alkane accumulation was insignificant with respect to toxicity in Saccharomyces cerevisiae cells, while C8 to C11 alkanes were cytotoxic [ 31].
Ms. Harris suggested that her mother focus on the consolations: a generous severance package and a not-insignificant accumulation of savings.
At the OLRs of 1.67 4.44 kg phenol/m3 d, the accumulation of volatile fatty acids (VFAs) was insignificant; whereas at the OLR of 5.11 kg phenol/m3 d, both the accumulation of VFAs and the washout of large hollow granules (average dp = 2.90 3.12 mm) occurred.
We do not exclude the possibility that the drop in intracellular ATP level may have a negative impact on biomass accumulation during aerobic large-scale cultivation, but we assume that this effect will be insignificant, since biomass accumulation of recombinant strain AS400/Pho8vac didn't differ substantially from the parental strain AS400 in the experiments we carried out.
Exposure of the rat erythrocytes to NaF was accompanied by progressive accumulation of peroxides, while superoxide (O2−) production was insignificant.
Insignificant degradation of transformation stress or accumulation of residual deformation is observed with increasing number of loading cycles.
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