The phrase "accumulation of inflammation" is correct and usable in written English.
It can be used in medical or scientific contexts to describe the buildup of inflammatory responses in a particular area of the body.
Example: "The doctor explained that the accumulation of inflammation in the joints could lead to chronic pain and mobility issues."
Alternatives: "build-up of inflammation" or "gathering of inflammation".
The average telomere length of peripheral leukocytes reflects not only the birth telomere length but also the accumulation of inflammation (6) and oxidative stresses of the body (7, 8).
Collectively, these results suggest that: i) expanding PLN protect the adjacent knee from arthritis; and ii) the loss of lymphatic drainage due to PLN collapse precipitates the accumulation of inflammation in the afferent joint that manifests as an arthritic flare.
It has been proposed that IPF likely results from the aberrant activation of alveolar epithelial cells after injury along with the accumulation of inflammation cells, which provoke the excessive proliferation of fibroblasts and exaggerated deposition of extracellular matrix (ECM) in the lung parenchyma, and finally leading to the destruction of lung parenchyma.
This study demonstrated that early intervention of HA is an effective protection against accumulation of inflammation-induced HIF-1α, iNOS, and MMP3 and might limit the erosive joint damage of arthritis.
This study demonstrated that early intervention of HA is an effective protection against accumulation of inflammation-induced HIF-1alpha, iNOS, and MMP3 to limit erosive damage in CFA-induced model of arthritis.
The suppressive effects on accumulation of inflammation-induced HIF-1α, iNOS, and MMP3 expressions in the synovium may be involved in the therapeutic mechanism of HA intervention used in the treatment of RA.
In colon cancer, the current hypothesis is that GTAs act analogously to the resolvins and protectins [ 38], protecting the body against the accumulation of chronic inflammation over time.
Indeed, Fxr KO mice have increased hepatic accumulation of p62, inflammation and developed spontaneous liver tumors, which are very similar to the autophagy-deficient mouse livers 127, 136, 137, 138, 139, 140.
In this review, we discuss three broad areas which have been explored that may be responsible for the combination of altered lung fibroblasts, loss of alveolar epithelial cells, and excessive accumulation of ECM: inflammation and immune mechanisms, oxidative stress and oxidative signaling, and procoagulant mechanisms.
When cancer is considered as a functional repair tissue for wound, the mystery of cancer incidence turnaround at very old age can be explained: wound incidence increases along with age due to the accumulation of injuries, inflammations, infections, toxins, and cell aging [ 48].
This article proposes a biomaterials-based therapeutic intervention for depletion of non-regulated cholesterol accumulation and inhibition of inflammation of macrophages.
