The phrase "accumulation of gain" is correct and usable in written English.
It can be used in contexts discussing financial growth, profit accumulation, or the gathering of benefits over time.
Example: "The company's strategy focused on the accumulation of gain through strategic investments and cost-cutting measures."
Alternatives: "build-up of profit" or "increase in earnings".
Most CRCs arise from adenomatous precursors, and accumulation of gain-of-function mutations in proto-oncogenes and loss-of-function mutations in tumor suppressor genes (TSGs) leads to progression of adenomatous lesions to carcinoma [2], [3], [4].
The occurrence and development of most colon cancers follows a stereotypical pattern of a progressive accumulation of gain- and loss of function mutations of oncogenes and tumor suppressor genes [ 37].
In many if not all tumors, acquisition of the full cancer phenotype may require the serial accumulation of gain-of-function mutations in oncogenes and loss-of-function mutations in tumor suppressor genes, as well as epigenetic changes.
Cancer progression is associated with genomic instability and an accumulation of gains and losses of DNA.
As described in the literature, accumulation of gains and/or losses in the genome can generate a pattern of chromosomal aberrations, which could constitute a molecular signature [ 13, 15- 18].
The accumulation of gains and/or losses in the genome of BRCA1-mutated BC can generate a pattern of chromosomal aberrations that could constitute a molecular signature, and it has been shown that BRCA1-mutated tumors develop a particular comparative genomic hybridization (CGH) profile [ 13, 15- 18].
This second T_GMAP file will likely be upgraded with the accumulation of additional gain calibration data, in the year 2013.
The phenotypic selection approach coupled with long testing phase often result in slow accumulation of genetic gain per unit time and cost [ 2].
We took advantage of this database to explore the accumulation of DNA gain or loss in serial pre-diagnostic samples from cases and to investigate factors associated with the detection of CNVs in exfoliated urothelial cells from tumor-free men.
At its core, the British program focused on an accumulation of marginal gains, Staff said.
His recent textbook Fundamentals of Boundary-Layer Meteorology offers the accumulation of insights gained during his academic career as a researcher and teacher in the field of boundary-layer meteorology.
