Sentence examples for accumulation of doses from inspiring English sources

23, 24 Current evidence shows that the most important triggering factor of TIPN is the accumulation of doses over the course of chemotherapy with a neurotoxic threshold of 1,000 mg/m for paclitaxel and 400 mg/m for docetaxel.

Accumulation of dose in this context is a critically important concept that has not been generally considered in occupational safety and health regulations to date and is the motivation for many of the recommendations in this mini-monograph.

Throughout this paper, we define exposures as intensity or concentration of substance, ignoring complications that arise from time-varying exposure patterns and accumulation of dose due to long-term exposure.

Attitudes such as these, and the accumulation of small doses of indifference towards intolerance and prejudice, are what bring about systematic discrimination.

Second, the accumulation of sublethal doses over several bites could kill the older mosquitoes.

34 This may lead to accumulation of high doses of deeper skin-penetrating UVA and contribute to melanoma risk.

An alternative explanation might be the potential reduction in the HRS effect by the accumulation of pulsed doses and the finite interpulse break time that might have partially triggered the repair mechanisms.

By pre-exposure computation, fixed time increments are transformed into a schedule with a predicted average accumulation of UV dose.

With the accumulation of UVB dose, more and more bare embryos are dead.

20 Microarray analysis showed that GBP1 gene expression increased along with the accumulation of total dose (Fig. 4b).

Dose normalization of the loading and maintenance doses indicated accumulation of AZD9773 following twice-daily dosing for 10 doses, with an accumulation ratio between 1.6 and 1.9.