Bio-AgNPs induces accumulation of autophagosomes (black arrow) and autolysosomes (white arrow) in cells treated with bio-AgNPs for 24 h (D).
By 43 weeks of life, Sucnr1−/− mice showed increased accumulation of lipofuscin (black arrows) while they were minimally detected in wild-type controls.
Ultrastructural analysis of epithelial cells showed a different structure of the Golgi and an accumulation of premature chylomicrons (arrows in Fig. 4E) within the Golgi apparatus in the Arfrp1 vil−/− epithelial cell.
(B) Liver histopathology 24 h after IP injection indicates accumulation of melanomacrophage centers (arrow).
(E ) Immunodetection with antibody specifically recognizing human Dystrophin on whole mount 2 dpf embryo shows punctate accumulation of exogenous huDys (arrow) suggestive of localization at the NMJ, in addition to fibre tips (arrowheads).
Arrowheads indicate cytoplasmic TDP43 accumulation, while arrows highlight nuclear clearance of TDP43.
Figure 7c shows a magnified image of the necrotic region with thin arrows indicating areas of high accumulation of red blood cells and thick arrows indicating areas of necrosis.
When a DC current of ~ 35 μA was passed through the BNNF, the carbon distribution changes to be non-uniform (Fig. 3b) with the carbon layer becoming thinner at position 1, indicated by a black arrow, and accumulation of carbon is observed around position 2, marked by a white arrow.
With PET/CT with 18F FDG in the right lobe of the liver, the focus of pathological accumulation of the radiopharmaceutical agent (red arrows) is visualized.
(A ) Immunofluorescence analysis of periostin in tendons of WT and Scx-Cre::Mmp14 lox/lox mice at E15.5, P0, and P10 of development show accumulation of periostin in epithelium (white arrows) of Scx-Cre::Mmp14 lox/lox tendons.
On the other hand, LF diet fed mice showed normal liver architecture after 3 months (Fig. 3a, a), scattered hepatic inflammatory cells in a small percentage of animals after 6 months (Fig. 3a, b, arrow) and accumulation of triglycerides in combination with hepatic inflammation after 12 months of LF diet treatment (Fig. 3a, c, arrows).
