With time, however, some cases accumulated, in which chronic pancreatitis involved the duodenal wall only with no or minor changes in the main (orthotopic) pancreas.
A completely separate pathway involves a large amount of calcium accumulating in cells, which may impair oxidative metabolism and begin further biochemical pathways that result in cell death.
Instead, the TfR was observed accumulating in vesicles, which were more pronounced in cells infected with the strains translocating EspG (WT or Δ espG + pEspG HA).
GA is the main metabolite accumulating in brain, which plays the major role in the inhibition of NaC3-mediated anaplerotic supply from astrocytes to neurons.
Often, too, the founders' wealth has been accumulated in bitcoin, which makes it unavoidable.
Mutations accumulated in genes which normally are rarely or non-expressed or non-mutating.
The irreversible genetic abnormalities accumulate in hepatocytes, which further cause disrupted gene expression, and finally lead to malignant transformation.
Due to changing environmental conditions and extreme use of agrochemical heavy metals are being accumulated in soils which are transferred to water system by leaching.
Once released into the environment, scandium gradually accumulates in soils, which leads to increased concentrations in soil particles, animals and humans.
p27kip, a UPP substrate accumulates in lenses which express K6W-Ub.
