The phrase "accumulating dna" is correct and usable in written English.
It can be used in contexts related to genetics, biology, or forensic science, where the collection or gathering of DNA samples is discussed.
Example: "The researchers are accumulating DNA samples from various species to study genetic diversity."
Alternatives: "collecting DNA" or "gathering DNA".
The human genome is constantly accumulating DNA changes through random mutation, though they seldom affect the actual structure of genes.
Endometrial cancers with the mutation had better outcomes, perhaps because the accumulating DNA damage is devastating to cancer cells.
However, this occurs as a late event during culture secondary to accumulating DNA damage [23]; it is therefore unlikely that the early MDM2 upregulation by AML1-ETO is secondary to p53 activation.
Biological aging or senescence may be due to accumulating DNA damage in somatic cells [1], [2], including erosion of telomeres, which may be caused by exposure to infectious and inflammatory diseases [3], [4] and other forms of oxidative stress [5], [6].
Alterations in the S-phase frequency upon DMC1 targeting are suggestive of accumulating DNA damage with reduced DMC1 expression.
Consequently, opportunity for accumulating DNA mutations is limited, resulting in relatively little genetic variation within the species.
Possible mechanisms include an increased replicative history and accumulated DNA damage arising from a defective DNA repair response in RA.
Our findings indicate that (1) exposure of SH-SY5Y cells to Mn promotes both the formation and accumulation of oxidative DNA damage, (2) SH-SY5Y cells with accumulated DNA damage are more likely to die via an apoptotic pathway and (3) the accumulated levels of DNA damage can be abrogated by the addition of exogenous chemical antioxidants.
This also concerns mitochondrial DNA (mtDNA), as it may accumulate DNA damage due to high level of reactive oxygen species (ROS) in its environs and less efficient DNA repair in comparison with nuclear DNA [ 10].
A deficiency in DNA repair capacity leads to greater DNA damage mediated by genotoxic agents and may result in accumulated DNA damage.
We attribute this phenomenon to a positive DEP response, which should accumulate DNA in the grooves.
