Your English writing platform
Discover LudwigExact(14)
Based on accumulated sequence data from the Los Alamos HIV Database (HIVDB) for HIV-1 subtype B Nef, we synthesized peptides corresponding to the consensus sequence and several naturally occurring mutants.
Thus, rather than directly assessing the degree of conservation among sequences, phylogenetic shadowing reveals regions that have accumulated sequence variation at a relatively slower rate, indicative of conserved function [46].
The minimum allele quality (accumulated sequence quality for every allele) was not lower than 20.
In our study, we investigated how epistatic interactions evolved as duplicate genes accumulated sequence divergence.
The accumulated sequence files were assembled with the Phrap program [ 69].
The accumulated sequence information resulted in a nearly 2000-fold coverage when expecting a genome of 3.5 Mb.
Similar(46)
Saturation plots were obtained by randomly shuffling the order of the filtered nucleotide or peptide sequences, and by calculating the number of distinct accumulated sequences at every 30th sequence.
The accumulated sequences were assembled using the Phrap program (http://phrap.org/).
Under the above parameters, randomized and non-coding sequences yielded AnABlast profiles with peaks rarely reaching a maximum of 70 accumulated sequences.
Setting optimal thresholds in AnABlast parameters (bit score threshold in sequence alignments and cut-off threshold of accumulated sequences) is nonetheless a key question.
By using a threshold of 30 in the score alignment, AnABlast peaks (accumulated sequences) generated in non-coding regions rarely reached the value of 70, while coding regions accumulated hundreds of sequences, yielding easily identifiable peaks (Fig. 3).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com