Sentence examples for accumulated resistance from inspiring English sources

The former factors are associated with archived resistance mutations and mandate a careful selection of drugs in case of a treatment change, even if the current resistance testing - if at all possible - may not reveal all accumulated resistance mutations.

Although gonorrhea can still be treated with antibiotics it has progressively accumulated resistance against many antibiotics like e.g. penicillin, ciprofloxacin, tetracycline, azithromycin and cefixime, and currently not many new antibiotics are available [2].

In addition, now that children are living longer, they need sequential regimens that will be active and overcome prior accumulated resistance for many decades, while promoting adherence and minimizing toxicity.

However, the significant negative correlation between accumulated resistance capacities with growth efficiency and niche width, as well as the substantial difference in growth efficiency and niche width among highly resistant versus susceptible isolates, suggests that costs of resistance can be substantial as multiple resistances accumulate.

Constant HAART selects HIV-1 resistant virus which may have accumulated resistances to all the available drugs.

Accordingly, some subtypes might accumulate resistance at different rates than subtype B at definite amino acid positions in PR and RT.

In the present study, ST11 KPC-KP also seemed to show dissemination advantage over other clones and be good colonizers to capture and accumulate resistance determinants.

Routine VL monitoring reduced the rate of accumulated genotypic resistance to commonly used ART in Uganda.

Our comparative genomics analysis reveals that isolates responsible for separate outbreaks, though closely related to one another, have independently accumulated antibiotic resistance genes, suggesting that there is little or no selection to retain these genes in-between outbreaks.

In treatment simplification, the risk of virological failures, demonstrated with regimens containing only NRTI as first-line [ 23], has been limited to patients who have experienced previous virological failures and have accumulated HIV resistance to this class [ 17, 18].

This study supported the hypothesis that subtype C accumulates resistance mutations at lower levels than subtype B. In our study, NNRTI was the only ARV class for which subtype C did not differ from subtype B with respect to the rate of acquisition of drug resistance mutations.